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Lab-based testing Best for: Transparent cash-pay labs

Sesame review

4.0/5

Sesame is a cash-pay healthcare marketplace: instead of a subscription or insurance, you pay one transparent up-front price for a doctor-ordered STD test (or a video visit) and give your sample at a partner lab. Results often come back in under 24 hours, and the price includes the lab order, collection and a results read. It's a great fit if you're uninsured and want the lowest no-surprises price; treatment is a separate booking. Here's our full review.

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Our rating
4.0/5
transparent cash pricing
Results
<24 hrs
often same next day
Visits from
$34
lab tests priced separately
Panel
6 STIs
comprehensive STD panel

Our verdict

Is Sesame worth it?

Sesame is our pick for the lowest-friction cash price. It's a marketplace, not a membership — you see one transparent price up front (no insurance, no surprise bills), pay for a doctor-ordered STD test or a $34+ video visit, and give your sample at a partner lab, often with results in under 24 hours. Its comprehensive panel covers six major STIs, and HSA/FSA is accepted. The trade-offs: exact lab prices aren't shown until you browse a specific listing, the panel doesn't include herpes, and there's no treatment in the same flow — a positive means booking a separate visit. For uninsured, price-conscious testing, it's excellent value.

Check prices at Sesame

The full review

Sesame in depth

Our hands-on take on what Sesame gets right, where it falls short, and how it stacks up.

Where the cash-pay math wins

Sesame's edge is that it's a marketplace, not a subscription. You pay one transparent up-front price for a doctor-ordered test — no insurance, no surprise bills — and that price already bundles the lab order, collection and a results read. With samples running through the Quest/Labcorp network, results often land in under 24 hours, which is among the fastest routes anywhere. For an uninsured, price-conscious tester, that combination is hard to beat, and HSA/FSA cards are accepted. If your goal is simply the cheapest defensible test, weigh it against a wider cost breakdown before you commit.

What it won't do for you

Two honest gaps keep Sesame at 4.0 rather than higher. First, the comprehensive panel covers six STIs but leaves out herpes (HSV), so if HSV matters to you, look elsewhere. Second, there's no treatment in the same flow — a positive means booking a separate video visit (from $34) with a clinician who can prescribe. If you'd rather close that loop in one place, PlushCare runs the full doctor-led loop with insurance, and prices aren't shown until you open a specific listing. You can also see how Sesame ranks against the field in our provider reviews.

How it scores

Sesame rated by category

We score every service on the things that actually matter, then weight them into one overall rating.

4.0

Overall · out of 5

Price & transparency

4.6/5

One up-front cash price, no insurance or surprise bills; among the cheapest routes.

Speed

4.6/5

Results often in under 24 hours from collection.

Accuracy

4.6/5

Doctor-ordered tests run through major partner labs (Quest/Labcorp network).

Panel breadth

3.8/5

Comprehensive 6-STI panel, but herpes isn't included.

Convenience

4.0/5

Marketplace model; you still visit a lab for the sample.

Care on positive

3.3/5

No treatment in the same flow — you book a separate visit if positive.

Is it right for you?

Who Sesame is — and isn't — for

Choose Sesame if…

  • You're uninsured and want the lowest transparent cash price
  • You want results fast — often under 24 hours
  • You want a doctor-ordered test without a subscription
  • You want to pay with HSA/FSA
  • You're comfortable booking a separate visit for treatment

Look elsewhere if…

  • You want herpes included in the panel (it isn't)
  • You want testing and treatment in one step
  • You want the price shown without browsing to a specific listing
  • You'd rather test at home

The honest take

Sesame pros & cons

Pros

  • Transparent cash pricing — no insurance, no surprise bills
  • Fast: results often in under 24 hours
  • Comprehensive panel covers six major STIs in one order
  • Price includes the lab order, collection and a results read
  • HSA/FSA accepted; video visits start at $34 if you want a clinician

Cons

  • Exact lab-test prices aren't shown until you open a specific listing
  • Comprehensive panel doesn't include herpes (HSV)
  • No treatment in the same flow — a positive needs a separate visit
  • Lab visit required (no at-home collection for the STD panels)
  • No insurance billing (cash-pay only; HSA/FSA accepted)

Step by step

How Sesame works

  1. 1

    Find your test

    Search the specific STD test or comprehensive panel on Sesame and pick a provider/lab slot at the listed cash price.

  2. 2

    Pay up front

    Pay the transparent price (HSA/FSA accepted) — it includes the lab order, collection and a results read.

  3. 3

    Visit a lab

    Give your sample at a partner lab (Quest/Labcorp network).

  4. 4

    Get results

    Results are delivered digitally, often within 24 hours, with next-step guidance; book a separate visit for treatment if needed.

What it costs

Sesame pricing

Cash-pay only; HSA/FSA accepted. Prices are transparent but shown per listing — individual STD tests and a comprehensive 6-STI panel are available; video visits start at $34.

Comprehensive STD Panel

HIV, syphilis, gonorrhea, chlamydia, hepatitis B and hepatitis C

Screens for

  • HIV
  • Syphilis
  • Gonorrhea
  • Chlamydia
  • Hepatitis B
  • Hepatitis C

Before you buy

Sesame: the fine print

Sample collection
Blood draw and/or urine at a partner lab
Insurance & payment
Cash-pay only; HSA/FSA accepted
Doctor consult
Optional video visits from $34; treatment is a separate booking
Privacy
HIPAA-compliant platform; cash-pay keeps results off insurance records

Good to Know

Sesame review FAQs

Common questions about Sesame — cost, accuracy, results and how it works.

What is Sesame?

Sesame is a cash-pay healthcare marketplace. Rather than billing insurance or charging a subscription, it lists transparent up-front prices for doctor-ordered lab tests and video visits, including STD testing — you pay once and give your sample at a partner lab.

How much does STD testing cost on Sesame?

Prices are transparent but shown per listing, so you'll see the exact amount when you select a specific test or the comprehensive panel. Video visits start at $34. It's cash-pay, with HSA/FSA accepted and no surprise bills.

How fast are results?

Results are often available in under 24 hours from collection — among the fastest routes — delivered digitally with next-step guidance.

What does the comprehensive panel cover?

HIV, syphilis, gonorrhea, chlamydia, hepatitis B and hepatitis C. Herpes (HSV) is not part of the comprehensive panel.

Does Sesame use insurance?

No — Sesame is intentionally cash-pay, which is how it keeps prices transparent and avoids surprise bills. HSA and FSA cards are accepted.

Can I get treated through Sesame?

Not in the same step as a lab test. If you test positive, you can book a separate Sesame video visit (from $34) with a clinician who may prescribe treatment.

Editorial standards

Medically reviewed · Updated

Reviewed by Jordan Vance, Lead Reviews Editor · Independent testing & product reviews

Evaluates at-home and lab STD-testing services hands-on against a fixed rubric — accuracy & lab credentials, price, privacy, turnaround and support — and discloses every affiliate relationship. Reviews are editorial, not medical advice; clinical claims are checked by our medical team.

3 Sources

Provider

  1. Sesame — STD testing https://sesamecare.com/lab-test/std-testing
  2. Sesame — official site https://sesamecare.com/

Clinical guidance

  1. CDC — STI screening recommendations https://www.cdc.gov/std/treatment-guidelines/screening-recommendations.htm

See how we review STD testing services — the categories we score, how we verify pricing, and why our affiliate links never change a rating.

Compare

How Sesame compares

Sesame versus the other STD testing services we've reviewed, side by side.

SesameThis review

4.0
Type
Lab visit
Results
Often under 24 hours from collection
Best for
Transparent cash-pay labs

MISTR

4.5
Type
Clinic & treat
Results
Provider-coordinated; medication ships after labs clear
Best for
Free PrEP & DoxyPEP, no in-person visit
Read MISTR review

LetsGetChecked

4.3
Type
At-home kit
Results
2–5 days after the lab receives your sample
Best for
Best overall at-home kit
Read LetsGetChecked review

STDcheck

4.3
Type
Lab visit
Results
1–2 days (secure online portal)
Best for
Fastest results & widest lab network
Read STDcheck review

Priority STD Testing

4.2
Type
Lab visit
Results
24–72 hours via secure online portal
Best for
Same-day testing with treatment
Read Priority STD Testing review

Q Care Plus

4.2
Type
Clinic & treat
Results
Provider-coordinated; first scripts/kits shipped after the visit
Best for
PrEP with built-in STI testing & treatment
Read Q Care Plus review

Visby Medical

4.2
Type
At-home kit
Results
About 30 minutes, read in the app
Best for
Fastest at-home result (30 min)
Read Visby Medical review

Walk-In Lab

4.2
Type
Lab visit
Results
1–2 days (single tests); 3–5 days (panels)
Best for
Widest test catalog & lab choice
Read Walk-In Lab review

HealthLabs

4.1
Type
Lab visit
Results
1–3 days (HIV RNA early detection 2–4 days)
Best for
Price match & broadest panels
Read HealthLabs review

Labcorp

4.1
Type
Lab + at-home
Results
1–4 days (lab) or 15–30 minutes (at-home rapid kits)
Best for
Big-lab testing, in person or at home
Read Labcorp review

CVS MinuteClinic

4.0
Type
Clinic & treat
Results
Rapid for some tests in-clinic; send-out lab results typically a few days
Best for
In-person evaluate & treat
Read CVS MinuteClinic review

FOLX Health

4.0
Type
Clinic & treat
Results
Up to about 5 business days for Quest lab results
Best for
LGBTQ+-affirming sexual health
Read FOLX Health review

myLAB Box

4.0
Type
At-home kit
Results
2–5 days after the lab receives your sample
Best for
Widest at-home panel & couples kits
Read myLAB Box review

Personalabs

4.0
Type
Lab visit
Results
24–48 hours via secure online portal
Best for
Physician-backed ordering
Read Personalabs review

Quest Diagnostics

4.0
Type
Lab + at-home
Results
2–5 days via the MyQuest app/portal
Best for
The national lab itself
Read Quest Diagnostics review

Ulta Lab Tests

4.0
Type
Lab visit
Results
24–48 hours via secure online portal
Best for
Quest catalog breadth
Read Ulta Lab Tests review

Wisp

4.0
Type
At-home kit
Results
3–5 days after the lab receives your sample
Best for
Test and treat in one place
Read Wisp review

Any Lab Test Now

3.9
Type
Lab visit
Results
3–5 business days after collection
Best for
Walk-in storefront testing
Read Any Lab Test Now review

PlushCare

3.9
Type
Clinic & treat
Results
1–5 business days, with doctor follow-up
Best for
Virtual doctor visit + treatment
Read PlushCare review

Private MD Labs

3.9
Type
Lab visit
Results
First results next day; complete results up to 7 business days
Best for
Low upfront cost & money-back
Read Private MD Labs review

Request A Test

3.8
Type
Lab visit
Results
Typically 1–3 business days via a secure online account
Best for
Established low-cost lab ordering
Read Request A Test review

Rapid STD Testing

3.7
Type
Lab visit
Results
1–2 business days via secure online portal
Best for
Concierge testing with treatment
Read Rapid STD Testing review

DirectLabs

3.6
Type
Lab visit
Results
24–48 business hours via the MyDLS portal
Best for
Cheap individual tests
Read DirectLabs review

Everlywell

3.6
Type
At-home kit
Results
About 5–7 days after the lab receives your sample
Best for
Retail pickup & wellness range
Read Everlywell review

Nurx

3.5
Type
At-home kit
Results
About 7 business days after the lab receives your sample
Best for
Billing insurance for an at-home kit
Read Nurx review
Compare all STD testing services

Top alternatives to Sesame

If Sesame isn't quite right, these are the closest options we'd point you to instead.

STDcheck

Want a dedicated STD storefront with set prices and an early-HIV option? STDcheck is built for it.

PlushCare

Want a doctor visit, lab order and treatment together (with insurance)? PlushCare does the full loop.