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Sexual health, clearly explained.

Symptom guides, condition deep-dives, testing how-tos and the latest research — written and fact-checked by our medical team. Plus free tools to help you take the next step.

Symptom guides

Which STDs cause your symptom?

Worried about a specific symptom? Start with the sign you're noticing — each guide covers the STIs behind it, how to test, and what to do next.

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  • Comparisons

    Contact Dermatitis vs Herpes vs STD Rash

    A new genital rash usually isn't herpes or any STD — contact dermatitis from latex condoms, soap, lube, or laundry detergent is a far more common cause. Contact dermatitis is an itchy, red, often symm

    Dr. Daniel Reyes, MD
  • Symptoms

    Tinea Versicolor vs STD Spots: Is This Rash an STI?

    Patchy discolored spots on your chest, back, or trunk are far more likely to be tinea versicolor — a harmless skin yeast — than an STI. Tinea versicolor isn't sexually transmitted and won't involve yo

    Dr. Daniel Reyes, MD
  • Comparisons

    4th Gen HIV Test vs Rapid Antibody Test

    A 4th-generation HIV test (an antigen/antibody lab test) and a rapid antibody test both look for HIV, but they detect it at different points. The 4th-gen test catches the p24 antigen — a viral protein

    Dr. Amara Okafor, MD MPH
  • Comparisons

    Anal Warts vs Hemorrhoids: How to Tell Apart

    Anal warts and hemorrhoids both show up as bumps near the anus, but they're entirely different problems. Anal warts are caused by HPV, a sexually transmitted virus, and usually feel like small, firm,

    Dr. Amara Okafor, MD MPH
  • Testing

    How to Ask Your Doctor for an STD Test

    To ask your doctor for an STD test, be direct: say you'd like to be screened, name any exposures or symptoms, and ask specifically which infections the panel covers. A clear request like "I'd like a f

    Dr. Amara Okafor, MD MPH
  • Audiences

    At-Home STI Test Kits for College Students: How They Work

    At-home STI test kits let college students collect their own urine, swab, or finger-prick blood sample privately in a dorm or apartment, mail it to a lab, and view results online — no clinic visit and

    Dr. Amara Okafor, MD MPH
  • Testing

    Can a Blood Test Detect All STDs?

    No, a single blood test can't detect all STDs. Blood draws find infections that circulate in the bloodstream — HIV, syphilis, and hepatitis — but chlamydia, gonorrhea, and trichomoniasis are caught fr

    Dr. Amara Okafor, MD MPH
  • Mpox

    Chancroid vs Syphilis: Telling the Ulcers Apart

    Chancroid and syphilis both cause genital ulcers, but the classic fork is pain: a chancroid ulcer is a soft, painful sore with tender, pus-filled groin nodes, while the primary syphilis chancre is a p

    Mark Riegel, MD
  • Comparisons

    Chlamydia vs Mycoplasma vs Ureaplasma

    Chlamydia and Mycoplasma genitalium are both bacteria that infect the urethra and cervix and cause overlapping symptoms — discharge, burning, and pelvic pain — but they're different organisms with dif

    Mark Riegel, MD

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