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  • Prevention

    Apretude: The HIV PrEP Shot Every 2 Months Explained

    Apretude (cabotegravir) is an injectable form of HIV PrEP — pre-exposure prophylaxis — given as a shot every two months instead of a daily pill. It's for HIV-negative adults and adolescents at risk th

    Dr. Daniel Reyes, MD
  • Prevention

    Does Circumcision Lower STD and HIV Risk?

    Yes, but only modestly and only for certain people. Large trials show male circumcision lowers a man's risk of getting HIV from vaginal sex and reduces some other STIs, but the effect is partial, does

    Dr. Daniel Reyes, MD
  • Comparisons

    Doxy PEP vs PrEP: What's the Difference?

    Doxy-PEP and PrEP aren't the same thing. Doxy-PEP is an antibiotic (doxycycline) taken after sex to lower the risk of certain bacterial STIs like syphilis and chlamydia. PrEP is medication taken to pr

    Mark Riegel, MD
  • Prevention

    Can DoxyPEP and PrEP Be Taken Together?

    Yes — Doxy-PEP and HIV PrEP can be taken together, and they're often used by the same people for the same reason: condomless sex. They work on completely separate threats. PrEP prevents HIV, while Dox

    Mark Riegel, MD
  • Prevention

    DoxyPEP and Antibiotic Resistance: What to Know

    Doxy-PEP (doxycycline post-exposure prophylaxis) is a single dose of the antibiotic doxycycline taken after sex to lower the risk of certain bacterial STIs. Because antibiotic use can drive resistance

    Mark Riegel, MD
  • Prevention

    Does DoxyPEP Work for Women? What Studies Show

    Doxy-PEP—a single dose of doxycycline taken after sex—has strong evidence for preventing bacterial STIs in gay and bisexual men and transgender women, but the one major trial in cisgender women did no

    Mark Riegel, MD
  • Hepatitis

    Can You Sexually Transmit Hepatitis A?

    Yes — you can sexually transmit hepatitis A, mainly through oral-anal contact, which is why it shows up in outbreaks among men who have sex with men. Hepatitis B is the more classic blood-borne and se

    Mark Riegel, MD
  • Hepatitis

    Hepatitis A Vaccine: Who Needs It and When

    The hepatitis A vaccine is a safe, highly effective shot that prevents hepatitis A virus (HAV) infection of the liver. The CDC recommends it for all children, for adults at higher risk — international

    Mark Riegel, MD
  • Hepatitis

    How Long Does Hepatitis Live Outside the Body?

    Hepatitis B virus (HBV) is unusually hardy outside the body. On dry surfaces — a shared razor, a toothbrush, a countertop with dried blood — it can stay infectious for days, even after the blood looks

    Mark Riegel, MD
  • Audiences

    Hepatitis A & B Vaccines for Gay & Bisexual Men

    Gay and bisexual men should get vaccinated against both hepatitis A and hepatitis B, ideally before any exposure. The hepatitis B vaccine is recommended for all adults aged 19–59 and for older adults

    Mark Riegel, MD
  • Prevention

    How Long Does PrEP Take to Work? Protection Timeline

    PrEP doesn't protect you the moment you swallow the first pill. Daily oral PrEP reaches its maximum protection in about 7 days for receptive anal sex, and about 21 days for receptive vaginal sex and i

    Dr. Daniel Reyes, MD
  • Prevention

    How to Prevent Mpox: Sex, Skin Contact & Vaccines

    To prevent mpox, avoid close skin-to-skin contact with anyone who has a rash, get the two-dose JYNNEOS vaccine if you're at increased risk, and limit anonymous or multiple partners during outbreaks. C

    Mark Riegel, MD
  • Prevention

    Can You Take PrEP On and Off? Seasonal Use Guide

    Yes, you can start and stop PrEP around periods when your risk goes up — like a vacation, a new relationship, or a stretch of casual dating — as long as you time it right and check in with a clinician

    Dr. Daniel Reyes, MD
  • Mpox

    Mpox Vaccine (Jynneos): Who Should Get It

    The JYNNEOS vaccine is a two-dose mpox vaccine recommended for people at increased risk of exposure, with the second dose given 28 days after the first CDC vaccines. It can also be used after a known

    Mark Riegel, MD
  • Prevention

    How to Clean Sex Toys to Prevent STDs

    To clean sex toys and lower STD risk, wash nonporous toys (silicone, glass, stainless steel) with warm water and mild soap after every use, dry them fully, and store them separately. Cover any shared

    Dr. Daniel Reyes, MD
  • Prevention

    How to Have Safer Sex While Trying to Conceive

    Safer sex while trying to conceive comes down to one honest conversation before you stop using condoms: get tested together, share your real results, and decide together what protection to use until y

    Dr. Daniel Reyes, MD
  • Prevention

    STD Prevention for Lesbian & Bisexual Women

    For lesbian and bisexual women, the single most effective STI prevention step is an open conversation with each partner about barriers, testing, and status — done before sex, framed as mutual care, an

    Dr. Daniel Reyes, MD
  • Prevention

    U=U Explained: Undetectable Equals Untransmittable

    U=U means Undetectable equals Untransmittable: a person living with HIV who takes antiretroviral therapy and keeps the virus at an undetectable level cannot pass HIV to a sexual partner. It's a preven

    Mark Riegel, MD
  • Prevention

    Can You Get an STD From Kissing?

    Yes — but only a couple of infections realistically spread through kissing, and the main ones are oral herpes (HSV) and, far less often, syphilis when a sore is present on the lips or mouth. Most STIs

    Dr. Daniel Reyes, MD
  • Prevention

    Can You Get an STD With a Condom On?

    Yes — you can still get an STI even when you use a condom correctly. Condoms cover the penis well, so they protect strongly against fluid-borne infections like chlamydia, gonorrhea, and HIV. But they

    Dr. Daniel Reyes, MD
  • Audiences

    PrEP for HIV Prevention: Who Should Take It & How

    PrEP (pre-exposure prophylaxis) is HIV medicine that people without HIV take to stay HIV-negative. Taken as prescribed, it cuts the risk of getting HIV from sex by about 99% and from injection drug us

    Dr. Daniel Reyes, MD
  • Prevention

    Can You Prevent HIV Without PrEP?

    Yes. You can lower your HIV risk a lot without PrEP by stacking proven tools: condoms used correctly, regular HIV testing, treatment-as-prevention (U=U — a partner with an undetectable viral load won'

    Dr. Daniel Reyes, MD
  • Testing

    STD Testing While on PrEP: What & How Often

    If you're on PrEP, plan on regular STD testing — an HIV test before you start and recurring check-ins while you stay on it. PrEP guards against HIV but not chlamydia, gonorrhea, or syphilis, so clinic

    Dr. Daniel Reyes, MD
  • Prevention

    What Happens If You Stop Taking PrEP?

    If you stop taking PrEP, the medicine clears from your body over days and your protection against HIV fades — you're no longer shielded once levels drop. Because PrEP works only while it's in your sys

    Dr. Daniel Reyes, MD
  • Audiences

    Transgender Women & HIV: Risk, PrEP & Hormone Interactions

    Transgender women face higher HIV risk than the general population, but the same proven tools protect them: PrEP, condoms, regular testing, and treatment-as-prevention. The most common worry — that es

    Dr. Daniel Reyes, MD
  • Prevention

    What to Do If a Condom Breaks During Sex

    If a condom breaks during sex, stop, withdraw, and clean up gently with water — don't douche or scrub. If HIV exposure is possible, call a clinic or ER about post-exposure prophylaxis (PEP) right away

    Dr. Daniel Reyes, MD
  • Prevention

    Best Condom Size Guide: How to Measure and Fit

    The best condom size is the one that fits snugly without pinching and stays put without rolling off — length covers from base to tip, and width matches your girth so the condom neither chokes nor slid

    Dr. Daniel Reyes, MD
  • Audiences

    DoxyPEP: How to Use Doxycycline After Sex to Prevent STIs

    DoxyPEP is a single dose of the antibiotic doxycycline — 200 mg taken within 72 hours after condomless sex — used to lower the risk of certain bacterial STIs, mainly syphilis and chlamydia CDC. It tar

    Mark Riegel, MD
  • Prevention

    Hepatitis B Vaccine for Adults: Schedule & Who Needs It

    The hepatitis B vaccine is recommended for all adults aged 19–59, and for adults 60 and older who have risk factors. The newer two-dose series (Heplisav-B) can be completed in about a month, while old

    Mark Riegel, MD
  • Hepatitis

    Hepatitis B Vaccine: Schedule, Doses, and Boosters

    The hepatitis B vaccine is a safe, highly effective shot series that teaches your immune system to block the hepatitis B virus (HBV) before it can infect your liver. ACIP recommends it for all adults

    Mark Riegel, MD
  • Prevention

    Do Spermicidal Condoms Prevent STDs?

    Spermicidal condoms don't prevent STDs any better than plain condoms — and the spermicide they use, nonoxynol-9 (N-9), can actually raise your HIV risk by irritating delicate genital tissue. A regular

    Dr. Daniel Reyes, MD
  • Prevention

    Why Do Condoms Break? Causes & How to Prevent It

    Condoms break for a handful of preventable reasons: trapped air in the tip, oil-based lubricant breaking down the latex, the wrong fit, heat or age weakening the material, and putting one on after sex

    Dr. Daniel Reyes, MD
  • Prevention

    Condom Types Explained: Latex, Polyurethane & More

    The main difference between condom types is the material: latex and polyurethane both block the genital fluids that carry HIV, gonorrhea, chlamydia, and trichomoniasis, while lambskin (natural-membran

    Dr. Daniel Reyes, MD
  • Comparisons

    Condoms vs PrEP: STD & HIV Protection

    Condoms and PrEP solve different problems. Condoms are a physical barrier that blocks many STDs — chlamydia, gonorrhea, syphilis, HIV — plus pregnancy. PrEP is a daily pill or shot that stops HIV only

    Dr. Daniel Reyes, MD
  • Audiences

    Menopause, Vaginal Dryness & STI Risk After 50

    Yes — vaginal dryness after menopause can make catching an STI easier, not harder. As estrogen falls, the vaginal lining thins, dries, and tears more easily during sex, and any tiny break in the tissu

    Dr. Amara Okafor, MD MPH
  • Prevention

    PEP vs PrEP: What's the Difference?

    PrEP and PEP both prevent HIV, but timing is everything: PrEP (pre-exposure prophylaxis) is medicine HIV-negative people take before possible exposure on an ongoing basis, while PEP is the emergency o

    Dr. Daniel Reyes, MD
  • Audiences

    Receptive Anal Sex: STI Risks & How to Lower Them

    Receptive anal sex carries the highest per-act HIV risk of any sexual activity — about 138 infections per 10,000 exposures, roughly 1 in 70, from a partner with untreated HIV CDC HIV estimates. The re

    Dr. Daniel Reyes, MD
  • Prevention

    STD Risk by Sexual Activity: Which Acts Are Riskiest

    STD risk varies sharply by activity. Receptive anal sex carries the highest per-act HIV risk — about 138 per 10,000 exposures — followed by insertive anal, receptive vaginal, then insertive vaginal se

    Dr. Daniel Reyes, MD
  • Prevention

    Where to Get PEP Fast Within 72 Hours

    To get PEP fast within 72 hours, go straight to an emergency room, urgent care, or any health care provider the same day — every hour matters and the clock starts at the moment of exposure, not when y

    Dr. Daniel Reyes, MD
  • Prevention

    Who Should Take PrEP? Eligibility Guide

    PrEP is for any HIV-negative person who has an ongoing chance of HIV exposure — through sex with partners whose status they don't know, with a partner living with HIV, or through sharing injection equ

    Dr. Daniel Reyes, MD
  • Prevention

    Truvada vs Descovy: Which PrEP Is Right for You?

    Truvada and Descovy are both daily PrEP pills that prevent HIV, but the key difference is who they're approved for: Truvada covers anyone at risk through sex or injection drug use, while Descovy is ap

    Dr. Daniel Reyes, MD
  • HIV/AIDS

    HIV PrEP: How It Works, Who Needs It, and How to Get It

    PrEP (pre-exposure prophylaxis) is medicine that HIV-negative people take before possible exposure to prevent infection. It comes as a daily pill or an injection given by a clinician, and when taken a

    Dr. Daniel Reyes, MD
  • Prevention

    How Effective Are Condoms at Preventing STDs?

    Used correctly and every single time, condoms are highly effective at preventing STDs spread through genital fluids — HIV, gonorrhea, chlamydia, and trichomoniasis. They offer less protection against

    Dr. Daniel Reyes, MD
  • Comparisons

    Gardasil vs Gardasil 9: HPV Vaccine Compared

    Gardasil and Gardasil 9 are both HPV vaccines, but they cover different numbers of strains. The original Gardasil protected against four HPV types (6, 11, 16, 18). Gardasil 9 adds five more cancer-cau

    Dr. Amara Okafor, MD MPH
  • Prevention

    PrEP Cost: How to Get It Free or Low-Cost

    PrEP (pre-exposure prophylaxis) can cost you nothing out of pocket. Most insurance plans cover it with no copay, and for the uninsured, manufacturer programs, federal initiatives, and clinic-based ass

    Dr. Daniel Reyes, MD
  • Prevention

    What Is PEP? Emergency HIV Prevention After Exposure

    PEP (post-exposure prophylaxis) is emergency HIV medicine you take after a possible exposure to stop the virus from establishing itself. You must start it within 72 hours of the exposure — and the soo

    Dr. Daniel Reyes, MD
  • Prevention

    Where to Get PrEP: Clinics, Telehealth & Online

    You can get PrEP from a primary care doctor, an STI or sexual-health clinic, a community health center, or an online telehealth service — many of which can prescribe within days. Every route starts wi

    Dr. Daniel Reyes, MD
  • Prevention

    What to Do After Unprotected Sex: Next Steps

    If you've just had unprotected sex and you're worried about HIV, the single most time-sensitive step is to ask a clinician about PEP (post-exposure prophylaxis) — HIV medicine that can stop the virus

    Dr. Daniel Reyes, MD
  • Prevention

    How Effective Is PrEP at Preventing HIV?

    PrEP is highly effective at preventing HIV when taken as prescribed. Taken consistently, it cuts the risk of getting HIV from sex by about 99% CDC, Talk PrEP Together and from injection drug use by at

    Dr. Daniel Reyes, MD
  • Prevention

    On-Demand PrEP (2-1-1): How the Dosing Works

    On-demand PrEP (2-1-1) is a way of taking oral PrEP pills around specific sex events instead of every day: two pills two to twenty-four hours before sex, one pill the next day, and one pill the day af

    Dr. Daniel Reyes, MD
  • Comparisons

    Truvada vs Descovy for PrEP: Compared

    Truvada and Descovy are both once-daily PrEP pills that prevent HIV before exposure, and both are highly effective. The big practical difference: Truvada covers risk from sex or injection drug use, wh

    Dr. Daniel Reyes, MD
  • Hepatitis

    Twinrix Vaccine: Hepatitis A and B

    The Twinrix vaccine protects against both hepatitis A and hepatitis B in one series of shots. It combines the standard hepatitis A and hepatitis B vaccines, given over a course of injections, so you b

    Mark Riegel, MD
  • Prevention

    Women Are Urged To Consider Female Condoms

    Internal condoms — the kind worn inside the vagina or anus, sometimes called "female" condoms — give women a barrier method they control, without needing a partner to put anything on. Used every time

    Dr. Daniel Reyes, MD
  • HPV

    What You Should Know About the HPV Vaccine for Boys

    The HPV vaccine for boys is Gardasil 9, a safe shot that prevents future infection with the HPV types behind most genital warts and several cancers — including throat cancer, which now outranks cervic

    Dr. Amara Okafor, MD MPH
  • Prevention

    What Is PrEP? How HIV Prevention Pills Work

    PrEP (pre-exposure prophylaxis) is medicine that HIV-negative people take before possible exposure to keep HIV from taking hold. It comes as a daily pill or a long-acting shot. Taken as prescribed, it

    Dr. Daniel Reyes, MD
  • Audiences

    DoxyPEP: How to Use Doxycycline After Sex to Prevent STIs

    Doxy-PEP (doxycycline post-exposure prophylaxis) is a single dose of the antibiotic doxycycline taken after condomless sex to lower the risk of certain bacterial STIs. The standard dose is 200 mg take

    Mark Riegel, MD
  • Prevention

    Best Lube for Condoms: What's Safe to Use

    The best lube for condoms is water-based or silicone-based — both are safe with latex and won't weaken it. Skip anything oil-based, like baby oil, lotion, petroleum jelly, or cooking oil, because oils

    Dr. Daniel Reyes, MD
  • Prevention

    PrEP Side Effects: What to Expect and When

    Most people on PrEP feel fine. The classic side effects are mild and short-lived: nausea, headache, stomach upset, or fatigue in the first few weeks as your body adjusts — usually fading on their own.

    Dr. Daniel Reyes, MD
  • Herpes

    How to Prevent Herpes Transmission to a Partner

    You can sharply lower the odds of passing herpes to a partner — though not to zero — by combining daily suppressive antiviral medication, consistent condom use, avoiding sex during outbreaks, and hone

    Dr. Daniel Reyes, MD
  • Comparisons

    PrEP vs PEP: HIV Prevention Differences

    PrEP is daily (or scheduled) medicine HIV-negative people take before possible exposure to prevent infection; PEP is an emergency course started after a single possible exposure. PrEP is ongoing preve

    Dr. Daniel Reyes, MD
  • Prevention

    What Is DoxyPEP? Antibiotic to Prevent STIs

    DoxyPEP is a single dose of the antibiotic doxycycline taken after sex to lower the risk of getting certain bacterial STIs. Standing for doxycycline post-exposure prophylaxis, it targets bacterial inf

    Mark Riegel, MD
  • Audiences

    PrEP for HIV Prevention: Pills vs Injectable Cabotegravir

    PrEP is daily or on-demand medicine that HIV-negative people take to prevent infection before exposure. You have two main forms: oral pills (Truvada or Descovy) and an injectable, cabotegravir (Apretu

    Dr. Daniel Reyes, MD
  • HIV & AIDS

    Truvada - A Pill That May Prevent HIV Infection

    Truvada is a daily prescription pill (emtricitabine/tenofovir disoproxil fumarate) taken by HIV-negative people to prevent HIV — a strategy called PrEP, or pre-exposure prophylaxis. Taken as prescribe

    Dr. Daniel Reyes, MD
  • HPV

    Is the Gardasil HPV Vaccine Safe?

    Yes — Gardasil 9 is safe and is one of the best-studied vaccines in use. It's monitored continuously, and the main reactions are mild and short-lived, like a sore arm. The bigger story is what it does

    Dr. Amara Okafor, MD MPH
  • HPV

    HPV Vaccine Side Effects: Updated Gardasil Safety Analysis

    The HPV vaccine's most common side effects are mild and short-lived: soreness, redness, or swelling at the injection spot, plus headache, low-grade fever, or fatigue for a day or two. The most notable

    Dr. Amara Okafor, MD MPH
  • HPV

    HPV Vaccine - Mandatory or Not?

    The HPV vaccine is not federally mandatory in the United States. No national law requires it; a handful of states and the District of Columbia tie it to school entry, usually with opt-outs. The CDC ro

    Dr. Amara Okafor, MD MPH
  • HPV

    HPV Vaccine for Adults: Is It Worth It After 26?

    Yes, the HPV vaccine can be worth it after 26. Gardasil 9 is approved through age 45, and adults aged 27 to 45 can get it after a shared-decision conversation with a clinician. It works best before ex

    Dr. Amara Okafor, MD MPH
  • HPV

    HPV Vaccine for Adults: Is the Gardasil Catch-Up Worth It?

    Yes, the HPV vaccine is approved and often worth it for adults through age 45 — but after age 26 it's a shared-decision call with your clinician, not a routine recommendation. Gardasil 9 prevents futu

    Dr. Amara Okafor, MD MPH
  • Prevention

    Can You Get an STD From Oral Sex?

    Yes — you can get an STD from oral sex. The most common are gonorrhea, chlamydia, syphilis, herpes (HSV-1 and HSV-2), HPV, and, less often, HIV. Throat and mouth infections are frequently silent, so s

    Mark Riegel, MD
  • Prevention

    Female Condoms: How to Use Internal Condoms

    A female condom (also called an internal condom) is a soft pouch you insert into the vagina or anus before sex. It lines the canal so semen and genital fluids never touch your skin directly. Used corr

    Dr. Daniel Reyes, MD
  • Prevention

    How to Use a Dental Dam for Safer Oral Sex

    A dental dam is a thin square of latex you place over the vulva or anus during oral sex so your mouth never touches genital fluids or skin directly. To use one, smooth it over the area before any cont

    Dr. Daniel Reyes, MD
  • Prevention

    How to Use a Condom Correctly Every Time

    To use a condom correctly every time, put a new one on the erect penis before any genital, oral, or anal contact, pinch the air from the tip as you unroll it all the way down, use only water- or silic

    Dr. Daniel Reyes, MD
  • Prevention

    How Safe Is My Contraceptive Method?

    Used every time and the right way, condoms are a highly effective barrier method for preventing the sexual spread of HIV, and they cut the risk of gonorrhea, chlamydia, trichomoniasis, and pregnancy C

    Dr. Daniel Reyes, MD
  • Hepatitis

    Hepatitis Vaccines

    The hepatitis B vaccine is the single best way to prevent hepatitis B, a blood-borne and sexually transmitted liver infection. ACIP recommends it for all adults aged 19–59, and for adults 60 and older

    Mark Riegel, MD