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  • Hepatitis

    Hepatitis C Reinfection: Can You Get It Again After Cure?

    Yes — you can get hepatitis C again after a cure. Direct-acting antiviral pills clear the virus in more than 95% of people WHO, but they don't leave behind immunity. Hepatitis C antibodies stay positi

    Mark Riegel, MD
  • Hepatitis

    How Long Does Hepatitis Live Outside the Body?

    Hepatitis B virus (HBV) is unusually hardy outside the body. On dry surfaces — a shared razor, a toothbrush, a countertop with dried blood — it can stay infectious for days, even after the blood looks

    Mark Riegel, MD
  • Audiences

    Hepatitis A & B Vaccines for Gay & Bisexual Men

    Gay and bisexual men should get vaccinated against both hepatitis A and hepatitis B, ideally before any exposure. The hepatitis B vaccine is recommended for all adults aged 19–59 and for older adults

    Mark Riegel, MD
  • Prevention

    How Long Does PrEP Take to Work? Protection Timeline

    PrEP doesn't protect you the moment you swallow the first pill. Daily oral PrEP reaches its maximum protection in about 7 days for receptive anal sex, and about 21 days for receptive vaginal sex and i

    Dr. Daniel Reyes, MD
  • Audiences

    How Often Should Gay & Bi Men Get STI Tested?

    For sexually active gay and bisexual men, the CDC recommends STI testing at least once a year, and every 3 to 6 months if you have multiple or anonymous partners, use recreational drugs during sex, or

    Dr. Amara Okafor, MD MPH
  • Prevention

    How to Prevent Mpox: Sex, Skin Contact & Vaccines

    To prevent mpox, avoid close skin-to-skin contact with anyone who has a rash, get the two-dose JYNNEOS vaccine if you're at increased risk, and limit anonymous or multiple partners during outbreaks. C

    Mark Riegel, MD
  • Testing

    How to Test for HPV in Men

    There's no FDA-approved HPV test for men. HPV tests aren't recommended to screen men, and no swab or blood test detects the virus in a man without symptoms. Diagnosis happens by looking — a clinician

    Dr. Amara Okafor, MD MPH
  • Prevention

    Can You Take PrEP On and Off? Seasonal Use Guide

    Yes, you can start and stop PrEP around periods when your risk goes up — like a vacation, a new relationship, or a stretch of casual dating — as long as you time it right and check in with a clinician

    Dr. Daniel Reyes, MD
  • Mpox

    Is Mpox an STD? How It Spreads Through Sex

    Mpox isn't classified as a traditional STD, but during the outbreak that began in 2022 it has spread mainly through close skin-to-skin contact, including sex. The monkeypox virus passes through direct

    Mark Riegel, MD
  • Mpox

    LGV Treatment: Doxycycline Course and Recovery

    LGV treatment is a long course of antibiotics: doxycycline taken by mouth twice a day for three weeks CDC STI Guidelines. That extended length is what sets it apart from the short course used for ordi

    Dr. Amara Okafor, MD MPH
  • Testing

    Does Medicaid Cover STD Testing?

    Yes — Medicaid covers STD testing. Federal Medicaid rules treat STI screening and diagnosis as preventive medical care, so the lab work for chlamydia, gonorrhea, HIV, syphilis, hepatitis, and trichomo

    Dr. Amara Okafor, MD MPH
  • Testing

    Can Minors Get STD Tested Without Parents?

    In most US states, minors can get tested for STIs without a parent's permission — every state allows some form of confidential testing and treatment for sexually transmitted infections for adolescents

    Dr. Amara Okafor, MD MPH
  • Mpox

    Mpox Treatment: Tecovirimat and How to Recover

    Most people with mpox recover on their own with supportive care — pain control, fluids, rest, and good lesion hygiene — over a few weeks. The antiviral tecovirimat (TPOXX) is reserved for severe disea

    Mark Riegel, MD
  • Mpox

    Mpox Vaccine (Jynneos): Who Should Get It

    The JYNNEOS vaccine is a two-dose mpox vaccine recommended for people at increased risk of exposure, with the second dose given 28 days after the first CDC vaccines. It can also be used after a known

    Mark Riegel, MD
  • NGU

    Is NGU Always From Sex? Non-STI Causes Explained

    No — non-gonococcal urethritis (NGU) isn't always from sex. Most cases trace to a sexually transmitted organism, but NGU is a syndrome, not a single infection: in roughly half of cases no organism is

    Mark Riegel, MD
  • NGU

    NGU Test: How Men Get Diagnosed With Urethritis

    An NGU test confirms nongonococcal urethritis — inflammation of the urethra that isn't caused by gonorrhea. Diagnosis takes two steps most pages skip past: first proving urethritis is present (white b

    Mark Riegel, MD
  • Treatment

    Pregnant & Allergic to Penicillin: STD Treatment

    If you're pregnant and allergic to penicillin and you test positive for syphilis, the answer is reassuring: you'll most likely be desensitized to penicillin under medical supervision and then treated,

    Dr. Amara Okafor, MD MPH
  • Comparisons

    Penile Yeast vs Herpes vs Balanitis: Rash Check

    A penile rash that itches, burns, or blisters is most often one of three things: a yeast infection (Candida overgrowth on the glans), genital herpes (an HSV viral infection), or balanitis (general inf

    Mark Riegel, MD
  • Prevention

    How to Avoid STDs in a New Relationship

    To avoid STDs in a new relationship, use condoms every time until you've both been tested, get tested together and share the results, and only stop barriers once you know each other's status. Add tool

    Dr. Daniel Reyes, MD
  • Treatment

    Azithromycin for STDs: Single-Dose vs Failure

    Azithromycin is an antibiotic still used for a handful of bacterial STIs, but it is no longer the go-to drug it once was. Current CDC guidance now favors doxycycline for chlamydia and reserves the sin

    Mark Riegel, MD
  • Audiences

    Dating Again After 50: STI Talks & Safer Sex

    Dating again after 50 means keeping safer-sex basics in play even though pregnancy is no longer a worry. Menopause thins and dries vaginal tissue, which makes small tears more likely during sex and ca

    Dr. Amara Okafor, MD MPH
  • Treatment

    Doxycycline for STDs: Uses, Dose & How to Take It

    Doxycycline is a tetracycline antibiotic used to treat several bacterial sexually transmitted infections, most commonly chlamydia. It's taken as a short course of oral pills, works by stopping bacteri

    Mark Riegel, MD
  • Prevention

    How to Clean Sex Toys to Prevent STDs

    To clean sex toys and lower STD risk, wash nonporous toys (silicone, glass, stainless steel) with warm water and mild soap after every use, dry them fully, and store them separately. Cover any shared

    Dr. Daniel Reyes, MD
  • Prevention

    How to Have Safer Sex While Trying to Conceive

    Safer sex while trying to conceive comes down to one honest conversation before you stop using condoms: get tested together, share your real results, and decide together what protection to use until y

    Dr. Daniel Reyes, MD