Chancroid and syphilis both cause genital ulcers, but the classic fork is pain: a chancroid ulcer is a soft, painful sore with tender, pus-filled groin nodes, while the primary syphilis chancre is a p
Mpox isn't classified as a traditional STD, but during the outbreak that began in 2022 it has spread mainly through close skin-to-skin contact, including sex. The monkeypox virus passes through direct
LGV treatment is a long course of antibiotics: doxycycline taken by mouth twice a day for three weeks CDC STI Guidelines. That extended length is what sets it apart from the short course used for ordi
Most people with mpox recover on their own with supportive care — pain control, fluids, rest, and good lesion hygiene — over a few weeks. The antiviral tecovirimat (TPOXX) is reserved for severe disea
The JYNNEOS vaccine is a two-dose mpox vaccine recommended for people at increased risk of exposure, with the second dose given 28 days after the first CDC vaccines. It can also be used after a known
Mpox symptoms usually start within 3 to 17 days of exposure, and almost everyone who gets sick does so within 21 days of contact CDC, signs & symptoms. The illness typically runs 2 to 4 weeks. The hal
A painful genital ulcer usually points to genital herpes or chancroid, while a painless one is the classic sign of primary syphilis. But pain is only the first clue — herpes, syphilis, and chancroid o
Swollen lymph nodes in the groin from an STI most often point to genital herpes, syphilis, or early HIV — all of which can cause tender or swollen glands as the immune system reacts to infection. But
Mpox symptoms center on a rash that looks like pimples or blisters — often painful or itchy — that can show up on the genitals, anus, mouth, hands, feet, or face. Since 2022, many people get just one
Mpox testing means swabbing an active skin lesion and running PCR to detect monkeypox virus DNA. There's no useful blood or antibody test for diagnosis, and you can't be tested before a sore appears —
A syphilis sore (chancre) is classically a single, painless, firm round ulcer at the site of infection, while mpox lesions are usually multiple, often painful or itchy, and frequently develop a dimple
Mpox and genital herpes can both cause painful sores on or near the genitals, but they're different infections with different culprits — mpox comes from the monkeypox virus, while herpes comes from HS
LGV and ordinary chlamydia are caused by the same bacterium — Chlamydia trachomatis — but different strains. LGV comes from the more aggressive L1–L3 serovars and causes severe, invasive disease like
LGV symptoms most often show up as rectal trouble — mucoid or bloody discharge, anal pain, constipation, and a constant urge to pass stool (tenesmus) — or as tender, usually one-sided swelling of the
Granuloma inguinale (donovanosis) is a rare bacterial STI caused by Klebsiella granulomatis that produces painless, slowly enlarging, beefy-red genital ulcers that bleed easily on contact. It's very u
Chancroid symptoms are one or more deep, painful genital ulcers along with tender, swollen lymph nodes in the groin that can fill with pus. The ulcers are soft and ragged, and they hurt — which sets c