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  • Comparisons

    Gonorrhea Treatment: Ceftriaxone vs Old Antibiotics

    Gonorrhea treatment is now a single injection of the antibiotic ceftriaxone — not the oral pills or drug combinations once used. The bacterium has grown resistant to nearly every older option, so curr

    Mark Riegel, MD
  • Comparisons

    Hepatitis A vs B vs C: How They Spread

    Hepatitis A and hepatitis B are both viral liver infections, but they differ in how they spread, how long they last, and whether they're curable. Hepatitis A spreads mainly through contaminated food o

    Mark Riegel, MD
  • Hepatitis

    Hepatitis B During Pregnancy: Protecting Your Baby

    Hepatitis B during pregnancy is highly manageable, and with the right steps your baby is very likely to stay infection-free. Every pregnancy is screened for the virus, and a baby born to an infected p

    Mark Riegel, MD
  • Prevention

    Hepatitis B Vaccine for Adults: Schedule & Who Needs It

    The hepatitis B vaccine is recommended for all adults aged 19–59, and for adults 60 and older who have risk factors. The newer two-dose series (Heplisav-B) can be completed in about a month, while old

    Mark Riegel, MD
  • Hepatitis

    Hepatitis B Vaccine: Schedule, Doses, and Boosters

    The hepatitis B vaccine is a safe, highly effective shot series that teaches your immune system to block the hepatitis B virus (HBV) before it can infect your liver. ACIP recommends it for all adults

    Mark Riegel, MD
  • Hepatitis

    Hepatitis B Window Period and How Soon to Test

    Hepatitis B has a long window: HBsAg, the marker of active infection, usually becomes detectable within several weeks of exposure, but symptoms average about 90 days out (range 60–150 days) CDC. For a

    Mark Riegel, MD
  • Hepatitis

    Hepatitis C Window Period: When to Test After Exposure

    The hepatitis C window period is the gap between exposure and when a test can reliably detect infection. An HCV RNA (viral) test can find the virus within a couple of weeks, while the standard antibod

    Mark Riegel, MD
  • Testing

    How Long Are STD Test Results Valid?

    An STD test result reflects your status only up to the point of your last possible exposure, minus the window period before infections become detectable. A negative is never permanent: any unprotected

    Dr. Amara Okafor, MD MPH
  • Testing

    Indeterminate STD Test Result: What It Means

    An indeterminate (or equivocal) STD result means the lab couldn't sort your sample cleanly into positive or negative — it landed in a gray zone. It isn't a diagnosis and it isn't an all-clear. The usu

    Dr. Amara Okafor, MD MPH
  • Audiences

    Mpox: Symptoms, Vaccine & Risk for Gay & Bi Men

    Mpox is a viral illness caused by the monkeypox virus, a relative of smallpox. It spreads mainly through close skin-to-skin contact — including sex — and causes a painful or itchy rash that often appe

    Mark Riegel, MD
  • NGU

    Can NGU Go Away on Its Own Without Treatment?

    NGU sometimes quiets down on its own, but "symptoms fade" is not the same as "infection cured." The organisms behind it — most often chlamydia or Mycoplasma genitalium — can persist silently, keep spr

    Mark Riegel, MD
  • PID

    PID and Pregnancy: Ectopic & Fertility Risks

    PID and pregnancy collide in two ways: pelvic inflammatory disease can scar the fallopian tubes, which raises the risk of an ectopic (tubal) pregnancy and can cause infertility, and the scarring compo

    Dr. Amara Okafor, MD MPH
  • NGU

    Sex With NGU: When Is It Safe After Treatment?

    After treatment for nongonococcal urethritis (NGU), wait until both you and any partners have finished the full course of antibiotics and have no symptoms before having sex again. CDC guidance points

    Mark Riegel, MD
  • Prevention

    Do Spermicidal Condoms Prevent STDs?

    Spermicidal condoms don't prevent STDs any better than plain condoms — and the spermicide they use, nonoxynol-9 (N-9), can actually raise your HIV risk by irritating delicate genital tissue. A regular

    Dr. Daniel Reyes, MD
  • Testing

    STD Testing After Anal Sex: Rectal Swabs Explained

    After receptive anal sex, the test that actually catches infection at the site of exposure is a rectal NAAT — a small swab of the rectum for chlamydia and gonorrhea — plus a blood draw for HIV and syp

    Dr. Amara Okafor, MD MPH
  • Testing

    STD Testing With No Symptoms After Cheating

    If you've cheated or been cheated on and feel fine, you can — and should — still get tested. Many STIs cause no symptoms, so how you feel tells you nothing about your status. Wait until the right wind

    Dr. Amara Okafor, MD MPH
  • Testing

    STD Testing for Trans & Nonbinary People

    STD testing for trans and nonbinary people works the same way it does for anyone — it should be based on the body parts you have and how you have sex, not on the gender on your chart. A urine sample o

    Dr. Amara Okafor, MD MPH
  • Treatment

    Do You Need a Prescription to Treat an STD?

    Yes, almost always. Curing or controlling an STI requires prescription medicine — a specific antibiotic, antiparasitic, or antiviral matched to the infection. No over-the-counter product or home remed

    Mark Riegel, MD
  • Treatment

    STD Treatment During Pregnancy: What's Safe?

    Most STIs can be treated safely during pregnancy, but the safe drug depends on the infection: penicillin remains the standard for syphilis (with desensitization if you're allergic), while doxycycline

    Dr. Amara Okafor, MD MPH
  • Treatment

    Can You Treat an STD Without Telling Your Partner?

    Yes — you can get tested and treated for an STI without telling your partner, because your medical care is confidential and no law forces you to disclose. But treating yourself in secret often backfir

    Mark Riegel, MD
  • Prevention

    Should I Get Tested After Every New Partner?

    Yes — testing after a new partner is one of the most reliable ways to know your status, because many STIs cause no symptoms and how you feel tells you nothing. A practical cadence is to test with each

    Dr. Amara Okafor, MD MPH
  • Prevention

    Why Do Condoms Break? Causes & How to Prevent It

    Condoms break for a handful of preventable reasons: trapped air in the tip, oil-based lubricant breaking down the latex, the wrong fit, heat or age weakening the material, and putting one on after sex

    Dr. Daniel Reyes, MD
  • Herpes

    Can You Get Herpes From Kissing?

    Yes, you can get herpes from kissing — but it's almost always oral herpes (HSV-1), not the genital type people usually worry about. The virus passes through contact with saliva or a cold sore on the l

    Dr. Daniel Reyes, MD
  • Chlamydia

    Chlamydia Complications in Women: PID & Infertility

    Untreated chlamydia in women can climb from the cervix into the uterus, fallopian tubes, and ovaries, causing pelvic inflammatory disease (PID) — and the inflammation that follows can scar the tubes,

    Dr. Amara Okafor, MD MPH