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  • HIV & AIDS

    Older Women are at Risk for HIV

    Yes — older women are at real risk for HIV. Menopause ends pregnancy worry, so condom use often drops, while thinning vaginal tissue can tear more easily during sex. Many women over fifty are never of

    Dr. Daniel Reyes, MD
  • Audiences

    Transgender Sexual Health & STI Screening Guide

    Transgender STI screening follows your anatomy and your sexual practices, not your gender marker. Screen by organ inventory: if you have a cervix, you may need cervical chlamydia and gonorrhea screeni

    Dr. Amara Okafor, MD MPH
  • NGU

    NGU vs Chlamydia: Symptoms, Tests & Treatment

    NGU (nongonococcal urethritis) and chlamydia aren't opposites — they overlap. NGU means inflammation of the urethra that isn't caused by gonorrhea, and chlamydia is one of its most common causes. So c

    Mark Riegel, MD
  • HIV & AIDS

    The Ethics of HIV Disclosure

    The ethics of HIV disclosure center on honesty, consent, and harm reduction: telling a sexual or needle-sharing partner about your status lets them make an informed choice, and modern science reshapes

    Dr. Daniel Reyes, MD
  • NGU

    NGU Causes: Mycoplasma, Ureaplasma & Trichomonas

    Nongonococcal urethritis (NGU) is urethral inflammation that isn't caused by gonorrhea. The most common identified cause is Chlamydia trachomatis , followed by Mycoplasma genitalium , and sometimes Tr

    Mark Riegel, MD
  • Audiences

    Can Teens Get STD Testing Without Parents Knowing?

    In most of the US, yes — teens can get STD testing without a parent finding out, because every state lets minors consent to confidential testing and treatment for sexually transmitted infections. The

    Dr. Amara Okafor, MD MPH
  • Mpox

    Mpox vs Syphilis Sore: Which One Do I Have?

    A syphilis sore (chancre) is classically a single, painless, firm round ulcer at the site of infection, while mpox lesions are usually multiple, often painful or itchy, and frequently develop a dimple

    Mark Riegel, MD
  • Mpox

    Mpox vs Herpes: How to Tell the Sores Apart

    Mpox and genital herpes can both cause painful sores on or near the genitals, but they're different infections with different culprits — mpox comes from the monkeypox virus, while herpes comes from HS

    Mark Riegel, MD
  • Comparisons

    Syphilis vs Herpes vs HPV Sores Compared

    Syphilis, herpes, and HPV can all show up as something on your skin down there, but they're caused by different organisms and behave very differently. A syphilis chancre is usually a single painless f

    Mark Riegel, MD
  • Syphilis

    Syphilis vs Herpes: Sores, Tests & Treatment

    Syphilis and genital herpes both cause genital sores, but they're fundamentally different. Syphilis is a bacterial infection that produces a single painless, firm sore and is curable with penicillin.

    Mark Riegel, MD
  • Molluscum Contagiosum

    Molluscum Contagiosum Treatment & Removal Options

    Most molluscum contagiosum clears on its own within several months to about a year, so watchful waiting is reasonable for many people. For genital bumps, clinicians usually recommend removal — cryothe

    Mark Riegel, MD
  • Syphilis

    Syphilis Treatment: Penicillin Shots & Cure

    Syphilis is cured with penicillin. For primary, secondary, or early latent disease, that means a single injection of benzathine penicillin G into the muscle; late or unknown-duration syphilis needs th

    Mark Riegel, MD
  • Syphilis

    Syphilis Test: Blood Tests, Timing & Accuracy

    A syphilis test is a blood test, and diagnosis takes two of them: a screening test (RPR or VDRL, or a treponemal antibody test) followed by a different confirmatory test. Antibodies can take up to two

    Mark Riegel, MD
  • Syphilis

    Syphilis Symptoms in Men vs Women

    Syphilis produces the same stages in men and women, but where the first sore lands differs. Men usually get a visible, painless chancre on the penis; women's chancres often sit inside the vagina or on

    Mark Riegel, MD
  • Syphilis

    Syphilis Symptoms: Chancre, Rash & Each Stage

    Syphilis symptoms unfold in stages. The first is usually a single painless sore (chancre) where the bacteria entered, about three weeks after exposure. Weeks later comes a rough rash, often on the pal

    Mark Riegel, MD
  • Syphilis

    Can You Get Syphilis Again After Treatment?

    Yes — you can absolutely get syphilis again after you've been treated and cured. A past infection gives you no immunity to Treponema pallidum , so a new exposure can reinfect you no matter how many ti

    Mark Riegel, MD
  • Mycoplasma Genitalium

    Mgen Testing: NAAT, Resistance Assay & When to Test

    Mgen testing uses an FDA-cleared NAAT (nucleic acid amplification test) on a urine sample or a swab to detect Mycoplasma genitalium 's genetic material. Because macrolide resistance is now common, cur

    Mark Riegel, MD
  • Syphilis

    Syphilis in Pregnancy & Congenital Syphilis

    Syphilis in pregnancy is a curable bacterial infection that can pass to the baby and cause miscarriage, stillbirth, or lifelong disability — known as congenital syphilis. The fix is straightforward: e

    Dr. Sarah Chen, MD
  • Syphilis

    How Syphilis Spreads: Sex, Kissing & Contact

    Syphilis spreads mainly through direct skin-to-skin contact with an active syphilis sore or rash during vaginal, anal, or oral sex, and from a pregnant person to their baby. The bacterium can't surviv

    Mark Riegel, MD
  • Mycoplasma Genitalium

    Mycoplasma Genitalium (Mgen): Symptoms, Causes & Treatment

    Mycoplasma genitalium (Mgen) is a sexually transmitted bacterium that causes urethritis in men and cervicitis in women, though it's often silent — especially in women. It's frequently mistaken for chl

    Mark Riegel, MD
  • Syphilis

    Can Syphilis Be Cured? Yes, Here's How

    Yes — syphilis is curable at every stage with the right antibiotics. The bacterium Treponema pallidum is reliably killed by penicillin, given as one injection for early infection or three weekly injec

    Mark Riegel, MD
  • Mycoplasma Genitalium

    Is Mycoplasma Genitalium Curable? Treatment & Resistance

    Mycoplasma genitalium is usually curable, but the word comes with a condition: cure now depends on matching the antibiotic to the strain. Because more than half of strains in many areas resist the old

    Mark Riegel, MD
  • Mycoplasma Genitalium

    Mgen Complications: PID, Infertility & Pregnancy Risks

    Mycoplasma genitalium can cause real complications when it's missed or undertreated: in women it can drive cervicitis up into pelvic inflammatory disease (PID), and emerging evidence links it to tubal

    Mark Riegel, MD