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  • Syphilis

    Syphilis RPR vs Treponemal Test Explained

    Syphilis testing uses two different kinds of blood tests. An RPR is a nontreponemal test that measures the body's reaction to tissue damage and can be tracked as a titer, while a treponemal test detec

    Dr. Amara Okafor, MD MPH
  • Syphilis

    Secondary Syphilis Rash: Palms, Soles & Body

    The secondary syphilis rash is a rough, red or reddish-brown eruption that classically appears on the palms and soles but can spread across the trunk and limbs. It's a sign the infection from Treponem

    Mark Riegel, MD
  • Syphilis

    Syphilis Rates by State 2023: Where Cases Are Rising Fastest

    In 2023 the US primary and secondary (P&S) syphilis rate reached 15.8 per 100,000 CDC AtlasPlus, 2023. Rates vary enormously by state: South Dakota, Washington DC, New Mexico, and Mississippi topped t

    Dr. Amara Okafor, MD MPH
  • Prevention

    Condom Types Explained: Latex, Polyurethane & More

    The main difference between condom types is the material: latex and polyurethane both block the genital fluids that carry HIV, gonorrhea, chlamydia, and trichomoniasis, while lambskin (natural-membran

    Dr. Daniel Reyes, MD
  • Comparisons

    Condoms vs PrEP: STD & HIV Protection

    Condoms and PrEP solve different problems. Condoms are a physical barrier that blocks many STDs — chlamydia, gonorrhea, syphilis, HIV — plus pregnancy. PrEP is a daily pill or shot that stops HIV only

    Dr. Daniel Reyes, MD
  • Treatment

    Expedited Partner Therapy (EPT): How to Treat Your Partner

    Expedited partner therapy (EPT) is the practice of treating the sex partners of someone diagnosed with chlamydia or gonorrhea by giving the patient a prescription or the medicine itself to hand to the

    Mark Riegel, MD
  • Audiences

    Group B Strep vs STIs in Pregnancy: What's Screened

    Group B strep (GBS) and STIs are screened at different times and for different reasons in pregnancy. The GBS swab is a routine late-pregnancy test for a common gut and vaginal bacterium that can be pa

    Dr. Amara Okafor, MD MPH
  • Audiences

    Menopause, Vaginal Dryness & STI Risk After 50

    Yes — vaginal dryness after menopause can make catching an STI easier, not harder. As estrogen falls, the vaginal lining thins, dries, and tears more easily during sex, and any tiny break in the tissu

    Dr. Amara Okafor, MD MPH
  • NGU

    NGU Symptoms in Men: Discharge, Burning & Tingling

    Nongonococcal urethritis (NGU) in men usually shows up as a thin, clear or cloudy (mucoid) discharge, burning or pain during urination, and an itchy or tingling feeling inside the tip of the penis. Ma

    Mark Riegel, MD
  • NGU

    NGU Treatment: Doxycycline vs Azithromycin

    NGU treatment is a defined course of antibiotics, and current CDC guidance recommends doxycycline taken twice daily for a week over a single dose of azithromycin — the shift reflects better cure rates

    Mark Riegel, MD
  • Prevention

    PEP vs PrEP: What's the Difference?

    PrEP and PEP both prevent HIV, but timing is everything: PrEP (pre-exposure prophylaxis) is medicine HIV-negative people take before possible exposure on an ongoing basis, while PEP is the emergency o

    Dr. Daniel Reyes, MD
  • Audiences

    Receptive Anal Sex: STI Risks & How to Lower Them

    Receptive anal sex carries the highest per-act HIV risk of any sexual activity — about 138 infections per 10,000 exposures, roughly 1 in 70, from a partner with untreated HIV CDC HIV estimates. The re

    Dr. Daniel Reyes, MD
  • Prevention

    STD Risk by Sexual Activity: Which Acts Are Riskiest

    STD risk varies sharply by activity. Receptive anal sex carries the highest per-act HIV risk — about 138 per 10,000 exposures — followed by insertive anal, receptive vaginal, then insertive vaginal se

    Dr. Daniel Reyes, MD
  • Symptoms

    STD Symptoms vs Yeast Infection: How to Tell Apart

    Vaginal itching, burning, and discharge get blamed on yeast more than anything else — but yeast is just one of several causes, and the others can look almost identical. The likeliest culprits are a va

    Dr. Amara Okafor, MD MPH
  • Testing

    Can You Get an STD Test Without Symptoms?

    Yes — you can and should get tested for STDs even with no symptoms. Most sexually transmitted infections cause no signs at all, so how you feel doesn't tell you your status; only a test does. A urine

    Dr. Amara Okafor, MD MPH
  • Testing

    How Much Does STD Testing Cost Without Insurance?

    Without insurance, STD testing can cost from nothing to a couple hundred dollars depending on where you go. Health departments, Planned Parenthood, and Title X clinics often test for free or on a slid

    Dr. Amara Okafor, MD MPH
  • Treatment

    How Much Does STD Treatment Cost Without Insurance?

    STD treatment without insurance is often free or low-cost. Public health departments, Planned Parenthood, and Title X clinics treat most infections on a sliding scale tied to your income, and many STI

    Dr. Amara Okafor, MD MPH
  • Symptoms

    STDs That Cause Bleeding Between Periods

    Bleeding between periods can be an early sign of a sexually transmitted infection — most often chlamydia or gonorrhea , which inflame the cervix and make it bleed easily, especially after sex. But spo

    Dr. Amara Okafor, MD MPH
  • Symptoms

    STDs That Cause White Spots or Patches on the Penis

    White spots or patches on the penis are most often not caused by an STI. The two harmless look-alikes — Fordyce spots and pearly penile papules — are normal anatomy. When an infection is the cause, th

    Dr. Amara Okafor, MD MPH
  • Symptoms

    What Types of STDs Cause Male Fertility?

    The STIs most likely to affect male fertility are chlamydia, gonorrhea, and Mycoplasma genitalium — all bacterial infections that can inflame the urethra and the tube behind the testicle. Each is ofte

    Dr. Amara Okafor, MD MPH
  • Prevention

    Where to Get PEP Fast Within 72 Hours

    To get PEP fast within 72 hours, go straight to an emergency room, urgent care, or any health care provider the same day — every hour matters and the clock starts at the moment of exposure, not when y

    Dr. Daniel Reyes, MD
  • Prevention

    Who Should Take PrEP? Eligibility Guide

    PrEP is for any HIV-negative person who has an ongoing chance of HIV exposure — through sex with partners whose status they don't know, with a partner living with HIV, or through sharing injection equ

    Dr. Daniel Reyes, MD
  • Comparisons

    Yeast Infection vs UTI: Symptom Comparison

    A vaginal yeast infection and a urinary tract infection feel different at their core: yeast brings external itching, soreness, and a thick white discharge, while a UTI brings internal burning with urg

    Dr. Amara Okafor, MD MPH
  • Relationships

    4 Tips To Sharing Your STD Status With A Partner

    Sharing your STD status with a partner comes down to four moves: bring it up at a calm, private moment before things get physical; agree to use condoms every time together; get tested — ideally togeth

    Dr. Daniel Reyes, MD